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According to a randomized crossover study from the US National Library of Medicine National Institutes of Health, a single dose of cannabidiol reduces blood pressure in healthy volunteers.

Cannabidiol (CBD) is the nonpsychoactive phytocannabinoid that is used in multiple sclerosis and intractable epilepsies. Recent preclinical studies now show that CBD has numerous cardiovascular benefits including reducing blood pressure (BP) response to stress. The study was investigating whether or not CBD Oil reduces BP in humans.

According to the report, nine healthy males volunteered and were given 600 mg of CBD or placebo in a randomized, placebo-controlled, double-blind, crossover study and results monitored using a finometer and laser Doppler.

Results showed a reduction in resting systolic BP (-6 mmHg; P <0.05) and stroke volume (-8 ml; P <0.05), with increased heart rate (+10 bpm; P <0.01), decreased stroke volume (-13ml; { <0.01).

METHODS. Nine healthy male volunteers were given 600 mg of CBD or placebo in a randomized, placebo-controlled, double-blind, crossover study. Cardiovascular parameters were monitored using a finometer and laser Doppler.

The data suggested that acute administration of CBD reduces resting BP and the BP increase to stress in humans with increased HR.

Further research will be used to determine whether CBD has a role in the treatment in cardiovascular disorders, the report concluded.CONCLUSIONS. This data shows that acute administration of CBD reduces resting BP and the BP increase to stress in humans, associated with increased HR. These hemodynamic changes should be considered for people taking CBD. Further research is required to establish whether CBD has a role in the treatment of cardiovascular disorders.